Prader-Willi Syndrome

Category:
Genetic Disorder

Prevalence:
In The US: About 1 in 10,000 to 30,000.

Also Called:
Prader-Labhart-Willi Syndrome, PWS

Resources:
Mayo Clinic

U.S. National Library of Medicine

WebMD

 

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Prader-Willi syndrome is a complex genetic condition that affects many parts of the body. In infancy, this condition is characterized by weak muscle tone (hypotonia), feeding difficulties, poor growth, and delayed development. Beginning in childhood, affected individuals develop an insatiable appetite, which leads to chronic overeating (hyperphagia) and obesity. Some people with Prader-Willi syndrome, particularly those with obesity, also develop type 2 diabetes mellitus (the most common form of diabetes).

People with Prader-Willi syndrome typically have mild to moderate intellectual impairment and learning disabilities. Behavioral problems are common, including temper outbursts, stubbornness, and compulsive behavior such as picking at the skin. Sleep abnormalities can also occur. Additional features of this condition include distinctive facial features such as a narrow forehead, almond-shaped eyes, and a triangular mouth; short stature; and small hands and feet. Some people with Prader-Willi syndrome have unusually fair skin and light-colored hair. Both affected males and affected females have underdeveloped genitals. Puberty is delayed or incomplete, and most affected individuals are unable to have children (infertile).

Prader-Willi Syndrome In The News

Disability Pride Parade NYC 2018: Start Time, Route, Registration

Read More    published: 07/11/2018

What Is Prader-Willi Syndrome? 380-Pound Girl With Rare Condition Crowned Pageant Queen

Read More    published: 03/27/2018

Video of Teen With Genetic Disorder Scoring Last-Minute Basket Goes Viral

Read More    published: 02/06/2017

Enzyme Deficiency in Brain Causes Extreme Hunger, Drives Obesity

Read More    published: 12/14/2016

'He's Close to Getting Diabetes': Katie Price Reveals Son Harvey, 14, Weighs 18 Stone Due to Genetic Condition

Read More    published: 12/15/2016

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