Muscular Dystrophy

Category:
Genetic Disorder

Prevalence:
In The US: Fewer than 200,000.

Resources:
Mayo Clinic

U.S. National Library of Medicine

WebMD

 

Donate

The muscular dystrophies (MD) are a group of more than 30 genetic diseases characterized by progressive weakness and degeneration of the skeletal muscles that control movement. Some forms of MD are seen in infancy or childhood, while others may not appear until middle age or later. The disorders differ in terms of the distribution and extent of muscle weakness (some forms of MD also affect cardiac muscle), age of onset, rate of progression, and pattern of inheritance.

Duchenne MD is the most common form of MD and primarily affects boys. It is caused by the absence of dystrophin, a protein involved in maintaining the integrity of muscle. Onset is between 3 and 5 years and the disorder progresses rapidly. Most boys are unable to walk by age 12, and later need a respirator to breathe. Girls in these families have a 50 percent chance of inheriting and passing the defective gene to their children. Boys with Becker MD (very similar to but less severe than Duchenne MD) have faulty or not enough dystrophin.

Facioscapulohumeral MD usually begins in the teenage years. It causes progressive weakness in muscles of the face, arms, legs, and around the shoulders and chest. It progresses slowly and can vary in symptoms from mild to disabling.

Myotonic MD is the disorder’s most common adult form and is typified by prolonged muscle spasms, cataracts, cardiac abnormalities, and endocrine disturbances. Individuals with myotonic MD have long, thin faces, drooping eyelids, and a swan-like neck.

Muscular Dystrophy In The News

Young Clemson Fan With Muscular Dystrophy Enjoys Game Again BC

Read More    published: 11/12/2018

Firefighters to Pass Boot to Squelch Dystrophy

Read More    published: 08/05/2018

Greality: Golf tournament to benefit Muscular Dystrophy Association

Read More    published: 07/22/2018

A LOCAL GYM SHOWS SOME MUSCLE FOR MUSCULAR DYSTROPHY

Read More    published: 06/17/2018

The Epitome of a Hardworking Farmer

Read More    published: 04/30/2018

Muscular Dystrophy Comments

Leave a New Comment